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ci service

Creative and Integrative

GI Longevity’s preclinical study center specialized in preclinical CRDO service

GI Longevity’s preclinical study center, a research institute for in vivo mouse efficacy test,

provides PK/PD and tox study consulting and CRDO service of new drug candidates and has various networks
related to efficacy evaluation for one stop preclinical study service

The state-of-the-art animal facility that enables GI Longevity to conduct multiple
CRDO projects simultaneously and quickly

Center for preclinical studies
Size
  • in vivo research center 1,700m2
  • Mouse breeding up to 13,000 mice
Location GI Longevity headquarter 1st basement
Approval
  • Approved by KFDA (2020.05.28)
  • Approved for LMO laboratory by ministry of science and ICT
Major research
  • Efficacy test of therapeutics using immuno deficient mouse and humanized mouse model
  • Behavioral testing room for CNS related analysis
  • Research on MoA of microbiome therapeutics

Why GI Longevity CRDO?

  • Specialized in humanized mouse model test and data packaging for clinical trial and technology transfer

  • One stop service from animal test design to immune profiling design and analysis

Preclinical study process

State of the art facility for systematic monitoring and managing preclinical studies

  • 인간화 마우스 이미지
  • 인간화 마우스 이미지
  • 인간화 마우스 이미지
  • IVIS 이미지
  • X-ray irradiator 이미지
  • 인간화 마우스 이미지
  • 인간화 마우스 이미지
  • 인간화 마우스 이미지
  • IVIS 이미지
  • X-ray irradiator 이미지

Animal test models for various kinds of diseases and tailored in vivo models
for CRDO service

Cancer

  • Breast cancer

  • Colon cancer

  • Lung cancer

  • Brain cancer

  • Liver cancer

  • Lymphoma cancer

  • Ovarian cancer

For more info

Renal disease

  • Acute renal failure : Ischemia-reperfusion injury model / Doxorubicin model

  • Chronic renal failure : Unilateral ureteral obstruction / Doxorubicin model / 5/6 nephrectomy model

For more info

Intestinal disease

  • Naive T cell transfer

  • DSS induced colitis

  • Oxazolone induced colitis

  • TNBS induced colitis

For more info

Liver disease

  • NASH(non-alcoholic steatohepatitis)

  • Hepatic fibrosis

For more info

Metabolic disease

  • Streptozotocin-induced model

  • Diet-induced model (Obesity)

For more info

CNS disease

  • Scopolamine-induced amnesia

  • Chronic restraint stress-induced depression model

  • Chronic constriction injury

  • Critical limb ischemia model

For more info

Immune disesae

  • Psoriasis

  • Atopic dermatitis

  • Passive cutaneous / systemic anaphylaxis

  • Food allergy / Food-induced anaphylaxis

  • Multiple sclerosis (EAE)

  • Allergic conjunctivitis

  • Rheumatoid arthritis

For more info

Respiratory / Circulatory disease

  • chronic obstructive pulmonary disease

  • Pulmonary fibrosis

  • Wound healing model (splint used mouse model)

  • Angiotensin II-induced atherosclerosis

For more info