µ+ Herbal therapy
Microbiome combined traditional Korean medicine therapy
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- Improving the gut
microbial ecosystem -
Herbal ingredients absorbed in the intestine
promote the growth of beneficial gut
bacteria and suppress harmful bacteria,
thereby supporting the immune system
and providing health benefits
- Improving the gut
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- Synergistic pharmacological
efficacy via interplay between microorganisms
and herbal ingredients -
Conversion of herbal ingredients in the
intestine by gut microbes induces
improved pharmacological efficacy
- Synergistic pharmacological
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- Influence of metabolites
on the efficacy of microorganisms and
herbal ingredients -
Some herbal ingredients not only contain
their own beneficial metabolites, but also
promote the production of new
metabolites by gut microbes
- Influence of metabolites
herbal supplements mixture in aged mice
C57BL/6, male
16 months
Monitoring grip strength
For a couple of decades, a number of studies have shown that gut microbiomes can modulate immune function in human body, and influence the pathophysiology of chronic diseases on energy metabolism, such as obesity and diabetes. Many of them cover the interaction between microbiomes and herbal medicines which are used in the prescription composition of various diseases in traditional Oriental medicine, including Korea. Prototype herbal ingredients are metabolized by the gut microbiome into substances with improved pharmacological activity that are absorbed into the body more readily. In addition, herbal ingredients help the gut microbiome produce beneficial metabolites by fermenting undigestible carbohydrates. In particular, some herbal ingredients help to restore gut microbiome dysbiosis caused by a western style diet, antibiotics abuse, and heavy drinking.
Traditional Korean herbal medicine has been prescribed to treat chronic diseases that have complicated modes of action for centuries. μ+ Herbal Therapy, the key concept of GI Longevity, focuses on interactions in the microbiome to provide evidence-based products for multi target /multi component approaches. It is challenging to maintain gut health with a few of selected probiotics, just as it would be difficult to maintain a garden full of beautiful blooms with a few flowers in the middle of the desert. The ultimate goal of μ+ Herbal Therapy is to develop novel microbiome combo therapeutics with traditional herbal medicines, with efficacy and safety proven through cutting-edge clinical trials.